Ahmad Solhan


Sarcopenia is often known as a condition of decreased hormone production, increased oxidative stress, difficulty in providing sufficient oxygen demand to cells, and impaired physical function. The findings in a study conducted by Choi DKK., (2020) indicated that circadian rhythm disorders are also associated with an increased risk of developing sarcopenia apart from aging. To overcome this situation, exercise has been asked to be one of the most appropriate strategies of muscle and muscle function. by successfully addressing problems associated with circadian rhythms and also positively impacting disorders of sarcopenia in humans.

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Al-Turk, W., & Al-Dujaili, E. A. (2016). Effect of age, gender and exercise on salivary dehydroepiandrosterone circadian rhythm profile in human volunteers. Steroids, 106, 19-25.

Anggriawan, J. (2017). Pengetahuan Instruktur Kebugaran di Wilayah Mojokerto Tentang Alat Olahraga Gym Ball. Jurnal Prestasi Olahraga, 1(1).

Ambarwati, R. (2017). Tidur, Irama Sirkardian Dan Metabolisme Tubuh. Jurnal Keperawatan, 10(1), 42-46.Cheng, P., & Drake, C. L. (2018). Psychological impact of shift work. Current sleep medicine reports, 4(2), 104-109.

Buchmann, N., Spira, D., Norman, K., Demuth, I., Eckardt, R., & Steinhagen-Thiessen, E. (2016). Sleep, muscle mass and muscle function in older people: a cross-sectional analysis based on data from the Berlin Aging Study II (BASE-II). Deutsches Ärzteblatt international, 113(15), 253.

Chang, S. F., & Lin, P. L. (2015). Frail phenotype and mortality prediction: a systematic review and meta-analysis of prospective cohort studies. International journal of nursing studies, 52(8), 1362-1374.

Choi, Y., Cho, J., No, M. H., Heo, J. W., Cho, E. J., Chang, E., & Kwak, H. B. (2020). Re-Setting the Circadian Clock Using Exercise against Sarcopenia. International Journal of Molecular Sciences, 21(9), 3106.

Choi, Y. I., Park, D. K., Chung, J. W., Kim, K. O., Kwon, K. A., & Kim, Y. J. (2019). Circadian rhythm disruption is associated with an increased risk of sarcopenia: A nationwide population-based study in Korea. Scientific reports, 9(1), 1-7.

Cruz-Jentoft, A. J., Bahat, G., Bauer, J., Boirie, Y., Bruyère, O., Cederholm, T., & Zamboni, M. (2019). Writing Group for the European Working Group on Sarcopenia in Older People 2 (EWGSOP2), and the Extended Group for EWGSOP2. Sarcopenia: revised European consensus on definition and diagnosis. Age Ageing, 48(1), 16-31.

Ekelund, U., Steene-Johannessen, J., Brown, W. J., Fagerland, M. W., Owen, N., Powell, K. E., & Lancet Sedentary Behaviour Working Group. (2016). Does physical activity attenuate, or even eliminate, the detrimental association of sitting time with mortality? A harmonised meta-analysis of data from more than 1 million men and women. The Lancet, 388(10051), 1302-1310.

Izquierdo, M., Casas-Herrero, A., Martínez-Velilla, N., Alonso-Bouzón, C., & Rodríguez-Mañas, L. (2017). An example of cooperation for implementing programs associated with the promotion of exercise in the frail elderly. European Erasmus+«Vivifrail» program.

Kim, J. H., & Duffy, J. F. (2018). Circadian rhythm sleep-wake disorders in older adults. Sleep medicine clinics, 13(1), 39-50.

Kline, C. E., & Youngstedt, S. (2017). Exercise and sleep. In Encyclopedia of Sleep (pp. 114-119). Elsevier Inc.

Larsson, L., Degens, H., Li, M., Salviati, L., Lee, Y. I., Thompson, W., & Sandri, M. (2019). Sarcopenia: aging-related loss of muscle mass and function. Physiological reviews, 99(1), 427-511.

Liberti, M. V., & Locasale, J. W. (2016). The Warburg effect: how does it benefit cancer cells. Trends in biochemical sciences, 41(3), 211-218

Matsumoto, T., Tanizawa, K., Tachikawa, R., Murase, K., Minami, T., Inouchi, M., ... & Chin, K. (2018). Associations of obstructive sleep apnea with truncal skeletal muscle mass and density. Scientific reports, 8(1), 1-8.

Nakao, R., Nikawa, T., & Oishi, K. (2017). The skeletal muscle circadian clock: current insights. ChronoPhysiology and Therapy, 7, 47-57.

Rubio-Arias, J. Á., Rodríguez-Fernández, R., Andreu, L., Martínez-Aranda, L. M., Martínez-Rodriguez, A., & Ramos-Campo, D. J. (2019). Effect of sleep quality on the prevalence of sarcopenia in older adults: A systematic review with meta-analysis. Journal of Clinical Medicine, 8(12), 2156.

Shaffer, N. C., Fabbri, E., Ferrucci, L., Shardell, M., Simonsick, E. M., & Studenski, S. (2017). Muscle quality, strength, and lower extremity physical performance in the Baltimore Longitudinal Study of Aging. The Journal of frailty & aging, 6(4), 183.

Sato, T., Ida, T., & Kojima, M. (2017). Role of biological rhythms in the performance of physical activity. The Journal of Physical Fitness and Sports Medicine, 6(3), 125-134.

Tahara, Y., Aoyama, S., & Shibata, S. (2017). The mammalian circadian clock and its entrainment by stress and exercise. The Journal of Physiological Sciences, 67(1), 1-10.

Tarazona-Santabalbina, F. J., Gómez-Cabrera, M. C., Pérez-Ros, P., Martínez-Arnau, F. M., Cabo, H., Tsaparas, K., ... & Viña, J. (2016). A multicomponent exercise intervention that reverses frailty and improves cognition, emotion, and social networking in the community-dwelling frail elderly: a randomized clinical trial. Journal of the American Medical Directors Association, 17(5), 426-433.

Van Hecke, L., Loyen, A., Verloigne, M., Van der Ploeg, H. P., Lakerveld, J., Brug, J., ... & Deforche, B. (2016). Variation in population levels of physical activity in European children and adolescents according to cross-European studies: a systematic literature review within DEDIPAC. International Journal of Behavioral Nutrition and Physical Activity, 13(1), 70.

Waning, D. L., Mohammad, K. S., Reiken, S., Xie, W., Andersson, D. C., John, S., ... & Guise, T. A. (2015). Excess TGF-β mediates muscle weakness associated with bone metastases in mice. Nature medicine, 21(11), 1262-1271.

Wiysonge, C. S., Bradley, H. A., Volmink, J., Mayosi, B. M., & Opie, L. H. (2017). Beta‐blockers for hypertension. Cochrane database of systematic reviews, (1).


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